Dr Bronwen Shaw
Research Summary
Dr Bronwen Shaw's research interests include immunogenetics and the impact of these factors on unrelated donor transplant outcome, graft selection, immune reconstitution (post cord blood transplantation), novel delivery of donor leukocyte infusions, graft versus host disease (GvHD) (use of extracorporeal photochemotherapy [ECP]) and late effects and long-term outcomes of transplantation.
She has investigated and published research on the impact of Human Leukocyte Antigen (HLA) matching (in particular a number of novel insights about HLA-DPB1 matching) on transplant outcome. One of the keys outcomes of these studies is to generate donor selection algorithms, and she has produced UK consensus guidelines dealing with this issue.
Dr Shaw also has a very active interest in donor safety and haemovigilance and, through her role as chair of the Clinical Working Group and a board member of the World Marrow Donor Association, is involved in international policy setting and recommendations for ethical and appropriate use of donors.
Biography
Dr Shaw is a clinical researcher with a joint post between The Royal Marsden and Anthony Nolan (UCL cancer centre) where she leads the Clinical Research Group in translational research in Blood and Marrow Transplantation.
She is funded by HEFCE as a Senior Clinical Lecture on a five year grant.
Dr Shaw is a member of the British Society for Blood and Marrow Transplantation (BSBMT) Executive Committee, and the Secretary of their Clinical Trials Committee. She is also a member of the Editorial Review Board of the Bone Marrow Transplantation journal, and is a regular reviewer for other journals.
Clinical Trials
Including immunogenetics and the impact of these factors on unrelated donor transplant outcome, graft selection, immune reconstitution (post cord blood transplantation), novel delivery of donor leukocyte infusions, graft versus host disease (use of ECP in GvHD), and late effects and longterm outcomes of transplantation.
