Research Interests

Current research projects/themes include:

• Evaluation and qualification of MRI biomarkers of diffuse adult and paediatric glioma, and neuroblastoma.
  
• The role of platelet-derived growth factor, and effects of putative PDGF antagonists, on tumour vascular morphology and function.
  
• Identification of in vivo biomarkers of tumour response to HIF-1 inhibition.
  
• Evaluation and qualification of susceptibility MRI derived biomarkers of tumours with velocity CT imaging of vascular corrosion casts.
  
• Imaging biomarkers in malignant bone disease.
  
• Non-invasive imaging of tumour elasticity using MR elastography.
  
• The use of intrinsic susceptibility (BOLD) MRI to assess tumour hypoxia.