Research Study
Childhood Overgrowth Study (COG)
Information for Professionals
The purpose of the Childhood Overgrowth Study (COG) is to identify, and better understand, the genetic factors that predispose to childhood overgrowth syndromes and/or asymmetric growth and to clarify the clinical features associated with these genetic factors. Such discoveries will facilitate a better understanding of the spectrum of childhood overgrowth phenotypes and will enable the development of guidelines for the diagnosis and management of affected individuals and their families.
Inclusion Criteria1. Overgrowth defined as height and/or head circumference ≥ 2 standard deviations above the mean (≥ 98th centile), and at least one additional clinical feature, such as: Learning difficulties Facial dysmorphism Congenital abnormality Skeletal abnormalities Neurological abnormalities Tumour 2. Asymmetric growth either static (for example, hemihypertrophy) or progressive (for example, Proteus). |
Study description, print version
Study documents required for patient recruitment
Enquiries
Margaret Warren-Perry PhD
Institute of Cancer Research
15 Cotswold Road, Sutton, Surrey SM2 5NG
Phone: 0208 722 4377
Fax: 0208 722 4359
Email: grs@icr.ac.uk
Principle Investigator
MREC: MREC/01/2/44
Breast and Ovarian Cancer
Our aim is to make use of the latest technological advancements in our unique sample series to elucidate the genetic architecture of breast and ovarian cancer.
