NSCCG Study
National Study of Colorectal Cancer Genetics (NSCCG)
The purpose of the National Study of Colorectal Cancer Genetics is to collect information from individuals who have been diagnosed with colorectal cancer who also have a family history of the condition, so that we can try and identify new hereditary factors (genes) that may lead to the development of colorectal cancer and further increase our understanding of why this condition develops and perhaps provide new targets for chemotherapy.
Study Type:
Observational Study
REC no: MREC/02/0/97
Disease: Colon; Rectum
Design Type: Genetic Epidemiology
Closure Date: 30/09/2015
Sample Size: 30,000 patients
Inclusion Criteria: Patients aged 18-59 at date of diagnosis, who have had a diagnosis of adenocarcinoma of the colon or rectum (large bowel) within the last five years. Appendix and Anal cancer is not included in the study. Patients must have a family history (defined as a parent, sibling or child also diagnosed with colorectal cancer)
Control recruitment has now closed.
Chief Investigator: Professor Richard Houlston
Current Progress
The study as of Christmas 2012 has recruited 25,363 patients
Newsletter
Download Christmas 2012 Newsletter for Research Nurses
NSCCG Christmas Update 2012 (234KB)
Contact Us
Further details please contact:
Mr Steven Penegar
Institute of Cancer Research
Section of Cancer Genetics
15 Cotswold Road
Sutton
SM2 5NG
Telephone: 020 8722 4471
Fax: 020 8722 4011
Email: Nsccg.Study@icr.ac.uk
Funders:CORE (formerly: Digestive Disorders Foundation); Cancer Research UK; The E.U.
Sponsor: Institute of Cancer Research, Surrey
NSCCG Documents
List of Documents required for Site set-up:
NSCCG_SSA Exemption confirmation 643KB
NSCCG Sponsorship Confirmation 140KB
List of Current Study Documents
NSCCG Participant Information Sheet v5 39KB
NSCCG Proband consent form v3 31KB
NSCCG Proband Registration Form v3 71KB
NSCCG Proband questionnaire v6 115KB
Substantial Amendment
List of Documents relating to Substantial Amendment 12
Documents relating to Amendment 12 where the upper age of eligibility has is 59 years of age at diagnosis and patients MUST have a family history of colorectal cancer. The PIS has been amended accordingly and space is provided for local hospital contact details to be inserted.
Notice of Substantial Amendment
NSCCG Participant Information Sheet v5
NSCCG Proband Registration Form v3