NSCCG Study
National Study of Colorectal Cancer Genetics (NSCCG)
The purpose of the National Study of Colorectal Cancer Genetics is to collect information from individuals who have been diagnosed with colorectal cancer, so that we can try and identify new hereditary factors (genes) that may lead to the development of colorectal cancer and further increase our understanding of why this condition develops and perhaps provide new targets for chemotherapy.
Study Type:
Observational
REC no: MREC/02/0/97
Disease: Colon; Rectum
Design Type: Genetic Epidemiology
Phase: This study is open to additional centres, and is SSA exempt.
Closure Date: 30/09/2015
Sample Size: 30,000
Inclusion Criteria: Patients aged 18-59 at date of diagnosis, who have had a diagnosis of adenocarcinoma of the colon or rectum (large bowel) within the last five years. Appendix and Anal cancer is not included in the study. Exclusion Criteria: Patients will be excluded if they do not meet the inclusion criteria. Controls will be excluded if they have a past or present history of cancer.
Chief Investigator: Professor Richard Houlston
Current Progress
The study as of December 3rd 2012 has recruited 25,247 patients and 4,284 controls
Newsletter
Download Christmas 2012 Newsletter for Research Nurses
NSCCG Christmas Update 2012 (234KB)
Contact Us
Further details please contact:
Mr Steven Penegar
Institute of Cancer Research
Section of Cancer Genetics
15 Cotswold Road
Sutton
SM2 5NG
Telephone: 020 8722 4471
Fax: 020 8722 4011
Email: Nsccg.Study@icr.ac.uk
Funders:CORE (formerly: Digestive Disorders Foundation); Cancer Research UK; The E.U.
Sponsor: Institute of Cancer Research, Surrey
NSCCG Documents
List of Documents required for Site set-up:
NSCCG Protocol Version 9.0 66KB
NSCCG_SSA Exemption confirmation 643KB
NSCCG Sponsorship Confirmation 140KB
List of Current Study Documents
NSCCG Participant Information Sheet - V4.0 March 2012 36KB
NSCCG Proband Consent Form - V.2.0 March 2008 20KB
NSCCG Control Consent Form - V.2.0 March 2008 19KB
NSCCG Control Information Sheet - V.2.0 November 2002 20KB
NSCCG Proband Questionnaire - V.5.0 November 2006 138KB
NSCCG Control Questionnaire - V.4.0 November 2006 48KB
NSCCG Pathology Request Letter - V.3.0 March 2006 27KB
NSCCG Proband Registration Form - V.2.0 June 2007 27KB
Substantial Amendment
List of Documents relating to Substantial Amendment 11
Documents relating to Amendment 11 where the upper age of eligibility has been reduced to 59 years of age at diagnosis. The PIS has been amended accordingly and space is provided for local hospital contact details to be inserted.
