Research Interest Overview
Ultrasound imaging provides essential in-vivo anatomical and functional information that can be used in cancer medicine for early detection, differential diagnosis, staging, biopsy guidance, treatment planning, treatment guidance, and the assessment of response to treatment. Our team’s work aims to enhance these functions by inventing, developing and applying ways of deriving new information from ultrasound signals. Optical methods complement ultrasound, with considerable potential for adding new information to that provided by ultrasound as, for example, in the multiphysics imaging method of photoacoustic imaging.
Our research is strongly translational, from basic physics and technical development, through preclinical studies to clinical evaluation.
The research interests of the Ultrasound and Optical Imaging team include:
- High frequency transducers and arrays
- Freehand elastography – breast imaging
- Freehand elastography – neurosurgical guidance
- Freehand elastography – a hybrid 3D strain image acquisition technique
- Quantitative elasticity imaging – elastic modulus and its use for ionising radiation dosimetry
- Quantitative elasticity imaging - porosity and permeability
- Quantitative elasticity imaging – slip elastography
- Quantitative elastography – improving lateral displacement and strain measurement
- High resolution and microscopic elastography
- Organ motion tracking for motion compensated therapy
- Clinical freehand reflection-mode photoacoustic imaging
- Illumination optimisation for freehand reflection-mode photoacoustic imaging
- Photoacoustic absorption spectroscopy and gold nanorods for molecular imaging
- Photoacoustic imaging and emission spectroscopy of tumour vascularisation
- Dynamic contrast-enhanced ultrasound (DCE-US) for tumour response
- Acoustically activated nanoparticle agents for molecular imaging
- Multimodality imaging of apoptosis
Research Interests
- High frequency transducers and arrays
- Freehand elastography – breast imaging
- Freehand elastography – neurosurgical guidance
- Freehand elastography – a hybrid 3D strain image acquisition technique
- Quantitative elasticity imaging – elastic modulus and its use for ionising radiation dosimetry
- Quantitative elasticity imaging - porosity and permeability
- Quantitative elasticity imaging – slip elastography
- Quantitative elastography – improving lateral displacement and strain measurement
- High resolution and microscopic elastography
- Organ motion tracking for motion compensated therapy
- Clinical freehand reflection-mode photoacoustic imaging
- Illumination optimisation for freehand reflection-mode photoacoustic imaging
- Photoacoustic absorption spectroscopy and gold nanorods for molecular imaging
- Photoacoustic imaging and emission spectroscopy of tumour vascularisation
- Dynamic contrast-enhanced ultrasound (DCE-US) for tumour response
- Acoustically activated nanoparticle agents for molecular imaging
- Multimodality imaging of apoptosis