Leukaemogenesis Team

Team Leader: Dr Eric CW So

Location: Brookes-Lawley Building, Sutton

Section: Section of Haemato-Oncology

The Leukaemogenesis team was established in Fall 2004 with the aim to understand the regulation of normal and malignant hematopoiesis. Using genetic, molecular, cellular and biochemical approaches, we are currently studying the roles of various oncogenic transcription factors and signalling pathways in both normal and cancer stem cells.

Find out more about:

• Homo-oligomerization of truncated transcription factors in human leukaemia
• Roles of Hox and Hox-cofactors in normal and malignant hematopoiesis
• Self-renewal pathways in hematopoietic and cancer stem cells
• Oncogenic mechanisms mediated by MLL oncoproteins