Section of Gene Function and Regulation
Chairman: Professor Peter Rigby FRS
Understanding gene function holds the best long-term promise for the rational design of selective reagents to interfere with the abnormal gene function that results in cancer. This research is the prerogative of basic biological science and since many of the genes that are disrupted or dysregulated in cancer are regulators of developmental and differentiation processes this programme of work is likely to provide significant insight into cancer mechanisms.
The overall strategy is to pursue basic research into normal developmental and differentiation processes and gain insight into the underlying mechanisms at the level of gene expression and also chromatin structure. We particularly focus on pathways, systems or processes with obvious cancer relevance.
In the Section of Gene Function and Regulation
Team Leader: Dr Amanda Swain
Team Leader: Professor Peter Rigby FRS
