Mesodermal Tissue Studies
Section: Section of Gene Function and Regulation
Novel Genes Involved in Somitogenesis
Using our own modification of differential display on presomitic mesoderm versus early somites we have isolated novel genes. This enabled us to successfully to identify a family of leucine rich membrane proteins (NLRR1 and FLRT3) whose expression pattern indicates a role in somite development. It will be necessary to knock-out each of these genes so as to define their function.
External funding: MYORES