Dr Jon Wilson
Tel: 020 7153 5122
Location: Chester Beatty Laboratories, London
Section: Section of Structural Biology
Research Interests
Publications
- Southall SM, Wong PS, Odho Z, Roe SM, Wilson JR. (2009) Structural basis for the requirement of additional factors for MLL1 SET domain activity and recognition of epigenetic marks. Mol Cell. 33(2), 181-91.
- Wilson, J.R. (2007) Targeting the JMJD2A histone lysine demethylase. Nat Struct Mol Biol.
14, 682-684.
Xiao B., Gamblin S.J. and Wilson J.R. (2006) Structure of SET domain protein lysine methyltransferases. In The Enzymes; 24. Protein methyltransferases. Eds. S.J. Clarke & F. Tamanoi. Elsevier / Academic Press. - Xiao,B., Jing, C., Kelly, G., Walker, P.A., Muskett, F.W., Frenkiel, T.A., Martin, S.R., Sarma, K., Reinberg, D., Gamblin, S.J. and Wilson, J.R. (2005) Specificity and Mechanism of the Histone Methyltransferase Pr-Set7. Genes & Development 19, 1444-1454.
- Chuikov S., Kurash J.K., Wilson J.R., Xiao B., Justin N., Ivanov G S., M cKinney K., Tempst P., Prives C., Gamblin S.J., Barlev N.A., and Reinberg D. (2004) Regulation of p53 Activity through Lysine Methylation. Nature 432, 353-360.
- Logan N, Delavaine L, Graham A, Reilly C, Wilson J, Brummelkamp TR, Hijmans EM, Bernards R, La Thangue NB. (2004) E2F-7: a distinctive E2F family member with an unusual organization of DNA-binding domains. Oncogene. 23, 5138-5150
- Blackburn, G.M., Gamblin, S.J. and Wilson J.R. (2003) Mechanism and control in biological amine methylation. (2003) Helvitica Chimica Acta. 86 (12) 4000-4006.
- Xiao, B., Jing, C., Wilson, J.R., Walker, P.A., Vasisht, N., Kelly, G., Howell, S.A., Taylor, I.A., Blackburn, G.M. & Gamblin, S.J. (2003) Structure and catalytic mechanism of the human histone methyltransferase SET7/9. Nature 421, 652-656.
- Xiao B., Wilson J.R. and Gamblin S.J. (2003) SET domains and histone methylation. Curr Opin Struct Biol. 13(6):699-705.
- Wilson, J.R., Caruana, D.J. and Gilardi, G. (2003) Engineering redox functions in a nucleic acid binding protein. Chem. Comm. 3 356-357
- Wilson J.R., Jing C., Walker P.A., Martin S.R., Howell, S.A., Blackburn, G.M. Gamblin S.J. and Xiao, B. (2002) Crystal Structure and Functional Analysis of the Histone Methyltransferase SET7/9, Cell 111, 105-115
- Brown N.L., Shih Y-C, Leang C., Glendinning K.J., Hobman J.L. and Wilson J.R. (2002) Mercury transport and resistance. Biochem Soc Trans 30 715-718.
