UK HRT

Disease site: Breast Cancer

Treatment Modality: Hormone Therapy

Status: In active follow-up

The HRT Trial was launched in March 2002 and had recruited 197 patients from 32 UK hospitals. The primary aim is to assess the effect of HRT on the long-term disease free and overall survival of breast cancer patients who are experiencing vasomotor symptoms. The effect of HRT on the relief of menopausal symptoms and quality of life of breast cancer patients will also be assessed along with cardiovascular and osteoporotic events. The trial was closed to further recruitment at the end of January 2004 owing to recruitment being slower that expected, however, patients taking part in the HRT Trial were still able to continue with their allocated treatment.

Chief Investigator: J. Marsden, Kings College Hospital, London.

Source of funding: Cancer Research UK.

ISRCTN: 29941643.

Publications

Marsden and Bliss, 1998. Br J Cancer 78: Suppl 2 36. Is clinical uncertainty sufficient amongst breast cancer surgeons for the implementation of a randomised trial of HRT in breast cancer patients?