SLNB

Disease site: Melanoma

Treatment Modality: Surgery

Status: In active follow-up

Primary Aim of the feasibility study is to determine patient acceptance of randomisation and compliance with the allocated surgery. Secondary Aims are to compare overall survival and disease-free survival in patients randomised to complete lymphadenectomy with that of patients in the observation arm. Approximately 120 patients will need to be approached in order to randomise 24 with a positive sentinel lymph node. Patients are recruited from 4 participating centres in the UK.

The SLNB Study is co-ordinated by the ICR - Clinical Trials & Statistics Unit and is supported by the NCRI Melanoma Clinical Studies Group.

The Study commenced September 2002 and is expected to close to recruitment Autumn 2006.

Chief Investigator: Dr Tim Eisen, Royal Marsden Hospital NHS Foundation

Source of funding: Cancer Research UK