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Wilkerson, P.M., Dedes, K.J., Pierre Samartzis, E., Dedes, I., Lambros, M.B., Natrajan, R., Gauthier, A., Piscuoglio, S., Töpfer, C., Vukovic, V., et al. (2017). Preclinical evaluation of the PARP inhibitor BMN-673 for the treatment of ovarian clear cell cancer. Oncotarget, Vol.8(4), pp. 6057-6066.  show abstract

Krasny, L., Paul, A., Wai, P., Howard, B.A., Natrajan, R.C. & Huang, P.H. (2016). Comparative proteomic assessment of matrisome enrichment methodologies. Biochemical journal, Vol.473(21), pp. 3979-3995.  show abstract

Miller, R.E., Brough, R., Bajrami, I., Williamson, C.T., McDade, S., Campbell, J., Kigozi, A., Rafiq, R., Pemberton, H., Natrajan, R., et al. (2016). Synthetic Lethal Targeting of ARID1A-Mutant Ovarian Clear Cell Tumors with Dasatinib. Molecular cancer therapeutics, Vol.15(7), pp. 1472-1484.  show abstract

Showeil, R., Romano, C., Valganon, M., Lambros, M., Trivedi, P., Van Noorden, S., Sriraksa, R., El-Kaffash, D., El-Etreby, N., Natrajan, R., et al. (2016). The status of epidermal growth factor receptor in borderline ovarian tumours. Oncotarget, Vol.7(9), pp. 10568-10577.  show abstract  full text

Campbell, J., Ryan, C.J., Brough, R., Bajrami, I., Pemberton, H.N., Chong, I.Y., Costa-Cabral, S., Frankum, J., Gulati, A., Holme, H., et al. (2016). Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines. Cell reports, Vol.14(10), pp. 2490-2501.  show abstract  full text

Wong, J.P., Todd, J.R., Finetti, M.A., McCarthy, F., Broncel, M., Vyse, S., Luczynski, M.T., Crosier, S., Ryall, K.A., Holmes, K., et al. (2016). Dual Targeting of PDGFRα and FGFR1 Displays Synergistic Efficacy in Malignant Rhabdoid Tumors. Cell reports, Vol.17(5), pp. 1265-1275.  show abstract

Maguire, S.L., Peck, B., Wai, P.T., Campbell, J., Barker, H., Gulati, A., Daley, F., Vyse, S., Huang, P., Lord, C.J., et al. (2016). Three-dimensional modelling identifies novel genetic dependencies associated with breast cancer progression in the isogenic MCF10 model. The journal of pathology, Vol.240(3), pp. 315-328.  show abstract

Natrajan, R., Sailem, H., Mardakheh, F.K., Arias Garcia, M., Tape, C.J., Dowsett, M., Bakal, C. & Yuan, Y. (2016). Microenvironmental Heterogeneity Parallels Breast Cancer Progression: A Histology–Genomic Integration Analysis. Plos medicine, Vol.13(2), pp. e1001961-e1001961.  show abstract  full text

Todd, J.R., Ryall, K.A., Vyse, S., Natrajan, R.C., Yuan, Y., Tan, A.C. & Huang, P.H. (2016). Systematic analysis of tumour cell-extracellular matrix adhesion identifies independent prognostic factors in breast cancer. Oncotarget, Vol.7(39), pp. 62939-62953.  show abstract

Morrison, E., Wai, P., Leonidou, A., Bland, P., Khalique, S., Farnie, G., Daley, F., Peck, B. & Natrajan, R. (2016). Utilizing Functional Genomics Screening to Identify Potentially Novel Drug Targets in Cancer Cell Spheroid Cultures. Journal of visualized experiments, (118).  show abstract

Weigelt, B., Ng, C.K., Shen, R., Popova, T., Schizas, M., Natrajan, R., Mariani, O., Stern, M.-., Norton, L., Vincent-Salomon, A., et al. (2015). Metastatic breast carcinomas display genomic and transcriptomic heterogeneity. Modern pathology, Vol.28(3), pp. 340-351.  show abstract

Schouten, P.C., Grigoriadis, A., Kuilman, T., Mirza, H., Watkins, J.A., Cooke, S.A., van Dyk, E., Severson, T.M., Rueda, O.M., Hoogstraat, M., et al. (2015). Robust BRCA1-like classification of copy number profiles of samples repeated across different datasets and platforms. Molecular oncology, Vol.9(7), pp. 1274-1286.  show abstract

Martelotto, L.G., De Filippo, M.R., Ng, C.K., Natrajan, R., Fuhrmann, L., Cyrta, J., Piscuoglio, S., Wen, H.-., Lim, R.S., Shen, R., et al. (2015). Genomic landscape of adenoid cystic carcinoma of the breast. The journal of pathology, Vol.237(2), pp. 179-189.  show abstract

Maley, C.C., Koelble, K., Natrajan, R., Aktipis, A. & Yuan, Y. (2015). An ecological measure of immune-cancer colocalization as a prognostic factor for breast cancer. Breast cancer research, Vol.17(1), p. 131.  show abstract  full text

Ng, C.K., Martelotto, L.G., Gauthier, A., Wen, H.-., Piscuoglio, S., Lim, R.S., Cowell, C.F., Wilkerson, P.M., Wai, P., Rodrigues, D.N., et al. (2015). Intra-tumor genetic heterogeneity and alternative driver genetic alterations in breast cancers with heterogeneous HER2 gene amplification. Genome biology, Vol.16(1), p. 107.  show abstract  full text

Bajrami, I., Frankum, J.R., Konde, A., Miller, R.E., Rehman, F.L., Brough, R., Campbell, J., Sims, D., Rafiq, R., Hooper, S., et al. (2014). Genome-wide Profiling of Genetic Synthetic Lethality Identifies CDK12 as a Novel Determinant of PARP1/2 Inhibitor Sensitivity. Cancer research, Vol.74(1), pp. 287-297.  show abstract

Natrajan, R., Wilkerson, P.M., Marchiò, C., Piscuoglio, S., Ng, C.K., Wai, P., Lambros, M.B., Samartzis, E.P., Dedes, K.J., Frankum, J., et al. (2014). Characterization of the genomic features and expressed fusion genes in micropapillary carcinomas of the breast. The journal of pathology, Vol.232(5), pp. 553-565.  show abstract  full text

Garcia-Murillas, I., Sharpe, R., Pearson, A., Campbell, J., Natrajan, R., Ashworth, A. & Turner, N.C. (2014). An siRNA screen identifies the GNAS locus as a driver in 20q amplified breast cancer. Oncogene, Vol.33(19), pp. 2478-2486.  show abstract  full text

Dryden, N.H., Broome, L.R., Dudbridge, F., Johnson, N., Orr, N., Schoenfelder, S., Nagano, T., Andrews, S., Wingett, S., Kozarewa, I., et al. (2014). Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C. Genome research, Vol.24(11), pp. 1854-1868.  show abstract

Piscuoglio, S., Ng, C.K., Martelotto, L.G., Eberle, C.A., Cowell, C.F., Natrajan, R., Bidard, F.-., De Mattos-Arruda, L., Wilkerson, P.M., Mariani, O., et al. (2014). Integrative genomic and transcriptomic characterization of papillary carcinomas of the breast. Molecular oncology, Vol.8(8), pp. 1588-1602.  show abstract  full text

Shiu, K.-., Wetterskog, D., Mackay, A., Natrajan, R., Lambros, M., Sims, D., Bajrami, I., Brough, R., Frankum, J., Sharpe, R., et al. (2014). Integrative molecular and functional profiling of ERBB2-amplified breast cancers identifies new genetic dependencies. Oncogene, Vol.33(5), pp. 619-631.  show abstract

Wetterskog, D., Wilkerson, P.M., Rodrigues, D.N., Lambros, M.B., Fritchie, K., Andersson, M.K., Natrajan, R., Gauthier, A., Palma, S.D., Shousha, S., et al. (2013). Mutation profiling of adenoid cystic carcinomas from multiple anatomical sites identifies mutations in the RAS pathway, but no KIT mutations. Histopathology, Vol.62(4), pp. 543-550.  show abstract

Eccles, S.A., Aboagye, E.O., Ali, S., Anderson, A.S., Armes, J., Berditchevski, F., Blaydes, J.P., Brennan, K., Brown, N.J., Bryant, H.E., et al. (2013). Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer. Breast cancer research, Vol.15(5), p. R92.  show abstract  full text

Horlings, H.M., Weigelt, B., Anderson, E.M., Lambros, M.B., Mackay, A., Natrajan, R., Ng, C.K., Geyer, F.C., van de Vijver, M.J. & Reis-Filho, J.S., et al. (2013). Genomic profiling of histological special types of breast cancer. Breast cancer research and treatment, Vol.142(2), pp. 257-269.  show abstract

Natrajan, R.C., Leonidou, A., Brough, R., Frankum, J., Wai, P.T., Ng, C.K., Reis-Filho, J.S., Lord, C.J. & Ashworth, A. (2013). Abstract S4-02: Integrated genomic analyses of members of protein kinase C family identifies subtype specific alterations as novel therapeutic targets. Cancer research, Vol.73(24 Supplement), pp. S4-02-S4-02.

Piscuoglio, S., Ng, C.K., Martelotto, L.G., Cowell, C.F., Natrajan, R., Bidard, F.-., Wilkerson, P.M., Mariani, O., Vincent-Salomon, A., Weigelt, B., et al. (2013). Abstract P4-04-08: Genomic and transcriptomic characterization of papillary carcinomas of the breast. Cancer research, Vol.73(24 Supplement), pp. P4-04-08-P4-04-08.

Natrajan, R. & Wilkerson, P. (2013). From Integrative Genomics to Therapeutic Targets. Cancer research, Vol.73(12), pp. 3483-3488.  show abstract

Wetterskog, D., Lopez-Garcia, M.A., Lambros, M.B., A'Hern, R., Geyer, F.C., Milanezi, F., Cabral, M.C., Natrajan, R., Gauthier, A., Shiu, K.-., et al. (2012). Adenoid cystic carcinomas constitute a genomically distinct subgroup of triple-negative and basal-like breast cancers. The journal of pathology, Vol.226(1), pp. 84-96.  show abstract

Patani, N., Lambros, M.B., Natrajan, R., Dedes, K.J., Geyer, F.C., Ward, E., Martin, L.-., Dowsett, M. & Reis-Filho, J.S. (2012). Non-existence of caveolin-1 gene mutations in human breast cancer. Breast cancer research and treatment, Vol.131(1), pp. 307-310.  show abstract

Geyer, F.C., de Biase, D., Lambros, M.B., Ragazzi, M., Lopez-Garcia, M.A., Natrajan, R., Mackay, A., Kurelac, I., Gasparre, G., Ashworth, A., et al. (2012). Genomic profiling of mitochondrion-rich breast carcinoma: chromosomal changes may be relevant for mitochondria accumulation and tumour biology. Breast cancer research and treatment, Vol.132(1), pp. 15-28.  show abstract

Duprez, R., Wilkerson, P.M., Lacroix-Triki, M., Lambros, M.B., MacKay, A., Hern, R.A., Gauthier, A., Pawar, V., Colombo, P.-., Daley, F., et al. (2012). Immunophenotypic and genomic characterization of papillary carcinomas of the breast. The journal of pathology, Vol.226(3), pp. 427-441.  show abstract

Natrajan, R., Mackay, A., Wilkerson, P.M., Lambros, M.B., Wetterskog, D., Arnedos, M., Shiu, K.-., Geyer, F.C., Langerød, A., Kreike, B., et al. (2012). Functional characterization of the 19q12 amplicon in grade III breast cancers. Breast cancer research, Vol.14(2), p. R53.  show abstract  full text

Geyer, F.C., Lacroix-Triki, M., Colombo, P.-., Patani, N., Gauthier, A., Natrajan, R., Lambros, M.B., Khalifeh, I., Albarracin, C., Orru, S., et al. (2012). Molecular evidence in support of the neoplastic and precursor nature of microglandular adenosis. Histopathology, Vol.60(6B), pp. E115-E130.  show abstract

Natrajan, R., Mackay, A., Lambros, M.B., Weigelt, B., Wilkerson, P.M., Manie, E., Grigoriadis, A., A'Hern, R., van der Groep, P., Kozarewa, I., et al. (2012). A whole-genome massively parallel sequencing analysis of BRCA1 mutant oestrogen receptor-negative and -positive breast cancers. The journal of pathology, Vol.227(1), pp. 29-41.  show abstract

Hernandez, L., Wilkerson, P.M., Lambros, M.B., Campion-Flora, A., Rodrigues, D.N., Gauthier, A., Cabral, C., Pawar, V., Mackay, A., A'Hern, R., et al. (2012). Genomic and mutational profiling of ductal carcinomas in situ and matched adjacent invasive breast cancers reveals intra-tumour genetic heterogeneity and clonal selection. The journal of pathology, Vol.227(1), pp. 42-52.  show abstract

Brough, R., Bajrami, I., Vatcheva, R., Natrajan, R., Reis-Filho, J.S., Lord, C.J. & Ashworth, A. (2012). APRIN is a cell cycle specific BRCA2-interacting protein required for genome integrity and a predictor of outcome after chemotherapy in breast cancer. The embo journal, Vol.31(5), pp. 1160-1176.  show abstract

Daemen, A., Wolf, D.M., Korkola, J.E., Griffith, O.L., Frankum, J.R., Brough, R., Jakkula, L.R., Wang, N.J., Natrajan, R., Reis-Filho, J.S., et al. (2012). Cross-platform pathway-based analysis identifies markers of response to the PARP inhibitor olaparib. Breast cancer research and treatment, Vol.135(2), pp. 505-517.  show abstract  full text

Ng, C.K., Gauthier, A., Mackay, A., Lambros, M.B., Rodrigues, D.N., Arnoud, L., Lacroix-Triki, M., Penault-Llorca, F., Baranzelli, M.C., Sastre-Garau, X., et al. (2012). Abstract PD05-08: Genomic characterisation of invasive breast cancers with heterogeneous HER2 gene amplification. Cancer research, Vol.72(24 Supplement), pp. PD05-08-PD05-08.

Gauthier, A., Lambros, M., Rodrigues, D.N., Arnould, L., Lacroix-Tikri, M., Penault-Llorca, F., Baranzelli, M.-., Sastre, X., Natrajan, R., Delattre, O., et al. (2012). Abstract 8: Genomic analyses of heterogeneous HER2 3+ invasive ductal carcinomas of the breast. Cancer research, Vol.72(8 Supplement), pp. 8-8.

Mackay, A.G., Natrajan, R., Maher, C., Lambros, M., Weigelt, B., Nava-Rodrigues, D., Wilkerson, P., CampionFlora, A., Kozarewa, I., Fenwick, K., et al. (2012). Abstract 5076: Integrative genomic and transcriptomic analysis of metaplastic carcinomas of the breast. Cancer research, Vol.72(8 Supplement), pp. 5076-5076.

Grigoriadis, A., Mackay, A., Noel, E., Wu, P., Natrajan, R., Frankum, J., Reis-Filho, J.S. & Tutt, A. (2012). Molecular characterisation of cell line models for triple-negative breast cancers. Bmc genomics, Vol.13(1), pp. 619-619.  show abstract  full text

Dedes, K.J., Natrajan, R., Lambros, M.B., Geyer, F.C., Lopez-Garcia, M.A., Savage, K., Jones, R.L. & Reis-Filho, J.S. (2011). Down-regulation of the miRNA master regulators Drosha and Dicer is associated with specific subgroups of breast cancer. Eur j cancer, Vol.47(1), pp. 138-150.  show abstract

Geyer, F.C., Lacroix-Triki, M., Savage, K., Arnedos, M., Lambros, M.B., MacKay, A., Natrajan, R. & Reis-Filho, J.S. (2011). beta-Catenin pathway activation in breast cancer is associated with triple-negative phenotype but not with CTNNB1 mutation. Modern pathol, Vol.24(2), pp. 209-231.  show abstract

Mackay, A., Weigelt, B., Grigoriadis, A., Kreike, B., Natrajan, R., A'Hern, R., Tan, D.S., Dowsett, M., Ashworth, A. & Reis-Filho, J.S., et al. (2011). Microarray-Based Class Discovery for Molecular Classification of Breast Cancer: Analysis of Interobserver Agreement. J natl cancer i, Vol.103(8), pp. 662-673.  show abstract  full text

Natrajan, R. & Reis, J.S. (2011). Next-generation sequencing applied to molecular diagnostics. Expert rev mol diagn, Vol.11(4), pp. 425-444.  show abstract

Brough, R., Frankum, J.R., Sims, D., Mackay, A., Mendes-Pereira, A.M., Bajrami, I., Costa-Cabral, S., Rafiq, R., Ahmad, A.S., Cerone, M.A., et al. (2011). Functional Viability Profiles of Breast Cancer. Cancer discov, Vol.1(3), pp. 260-273.  show abstract

Wilkerson, P.M., Dedes, K.J., Wetterskog, D., Mackay, A., Lambros, M.B., Mansour, M., Frankum, J., Lord, C.J., Natrajan, R., Ashworth, A., et al. (2011). Functional characterization of EMSY gene amplification in human cancers. J pathol, Vol.225(1), pp. 29-42.  show abstract

Lambros, M.B., Wilkerson, P.M., Natrajan, R., Patani, N., Pawar, V., Vatcheva, R., Mansour, M., Laschet, M., Oelze, B., Orr, N., et al. (2011). High-throughput detection of fusion genes in cancer using the Sequenom MassARRAY platform. Laboratory investigation; a journal of technical methods and pathology, Vol.91(10), pp. 1491-1501.  show abstract

Lambros, M.B., Wilkerson, P.M., Natrajan, R., Patani, N., Pawar, V., Vatcheva, R., Mansour, M., Laschet, M., Oelze, B., Orr, N., et al. (2011). High-throughput detection of fusion genes in cancer using the Sequenom MassARRAY platform. Laboratory investigation, Vol.91(10), pp. 1491-1501.  show abstract

Williams, R.D., Al-Saadi, R., Natrajan, R., Mackay, A., Chagtai, T., Little, S., Hing, S.N., Fenwick, K., Ashworth, A., Grundy, P., et al. (2011). Molecular profiling reveals frequent gain of MYCN and anaplasia-specific loss of 4q and 14q in wilms tumor. Genes, chromosomes and cancer, Vol.50(12), pp. 982-995.  show abstract

Ha, K.C., Lalonde, E., Li, L., Cavallone, L., Natrajan, R., Lambros, M.B., Mitsopoulos, C., Hakas, J., Kozarewa, I., Fenwick, K., et al. (2011). Identification of gene fusion transcripts by transcriptome sequencing in BRCA1-mutated breast cancers and cell lines. Bmc medical genomics, Vol.4(1), p. 75.  show abstract  full text

Wetterskog, D., Shiu, K.-., Chong, I., Meijer, T., Natrajan, R., Lord, C.J., Ashworth, A. & Reis-Filho, J.S. (2011). Abstract 4987: Identification of novel genes and pathways involved in resistance to HER2-targeting agents in breast cancer. Cancer research, Vol.71(8 Supplement), pp. 4987-4987.

Wilkerson, P., Dedes, K.J., Wetterskog, D., Natrajan, R., Lambros, M.B., Mackay, A., Lord, C.J., Ashworth, A. & Reis-Filho, J.S. (2011). Abstract 3917: EMSY amplification and overexpression is not associated with defective homologous recombination and does not predict sensitivity to cisplatin or PARP inhibitors. Cancer research, Vol.71(8 Supplement), pp. 3917-3917.

Chong, I., Wetterskog, D., Shiu, K.-., Meijer, T., Natrajan, R., Maryou, L., Reis-Filho, J., Lord, L.J., David, C. & Ashworth, A., et al. (2011). Abstract 3039: Identification of a novel biomarker of resistance to lapatinib common to both breast and oesophagogastric cancer. Cancer research, Vol.71(8 Supplement), pp. 3039-3039.

Natrajan, R., Maher, C.A., Lambros, M.B., Pawar, V., Wetterskog, D., Marchio, C., Barbashina, V., Geyer, F.C., Fenwick, K., Kozarewa, I., et al. (2011). Abstract 4829: Massively parallel RNA sequencing analysis of micropapillary carcinomas of the breast. Cancer research, Vol.71(8 Supplement), pp. 4829-4829.

Daemen, A., Wolf, D.M., Korkola, J.E., Griffith, O.L., Frankum, J.R., Jakkula, L.R., Wang, N.J., Natrajan, R., Reis-Filho, J.S., Lord, C.J., et al. (2011). P1-06-22: Identification of Biomarkers in Breast Cancer for Prediction of Response to PARP Inhibitor Olaparib. Cancer research, Vol.71(24 Supplement), pp. P1-06-22-P1-06-22.

Tan, D.S., Iravani, M., McCluggage, W.G., Lambros, M.B., Milanezi, F., Mackay, A., Gourley, C., Geyer, F.C., Vatcheva, R., Millar, J., et al. (2011). Genomic Analysis Reveals the Molecular Heterogeneity of Ovarian Clear Cell Carcinomas. Clin cancer res, Vol.17(6), pp. 1521-1534.  show abstract

Sharpe, R., Pearson, A., Herrera-Abreu, M.T., Johnson, D., Mackay, A., Welti, J.C., Natrajan, R., Reynolds, A.R., Reis, J.S., Ashworth, A., et al. (2011). FGFR Signaling Promotes the Growth of Triple-Negative and Basal-Like Breast Cancer Cell Lines Both In Vitro and In Vivo. Clin cancer res, Vol.17(16), pp. 5275-5286.  show abstract

Robinson, D.R., Kalyana-Sundaram, S., Wu, Y.-., Shankar, S., Cao, X., Ateeq, B., Asangani, I.A., Iyer, M., Maher, C.A., Grasso, C.S., et al. (2011). Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer. Nature medicine, Vol.17(12), pp. 1646-1651.  show abstract  full text

Tanas, M.R., Sboner, A., Oliveira, A.M., Erickson-Johnson, M.R., Hespelt, J., Hanwright, P.J., Flanagan, J., Luo, Y.L., Fenwick, K., Natrajan, R., et al. (2011). Identification of a Disease-Defining Gene Fusion in Epithelioid Hemangioendothelioma. Sci transl med, Vol.3(98),  show abstract

Xu, H.L., Yan, M., Patra, J., Natrajan, R., Yan, Y.Q., Swagemakers, S., Tomaszewski, J.M., Verschoor, S., Millar, E.K., van der Spek, P., et al. (2011). Enhanced RAD21 cohesin expression confers poor prognosis and resistance to chemotherapy in high grade luminal, basal and HER2 breast cancers. Breast cancer res, Vol.13(1),  show abstract  full text

Turner, N., Pearson, A., Sharpe, R., Lambros, M., Geyer, F., Lopez-Garcia, M.A., Natrajan, R., Marchio, C., Iorns, E., Mackay, A., et al. (2010). FGFR1 Amplification Drives Endocrine Therapy Resistance and Is a Therapeutic Target in Breast Cancer. Cancer research, Vol.70(5), pp. 2085-2094.  show abstract

Weigelt, B., Geyer, F.C., Natrajan, R., Lopez-Garcia, M.A., Ahmad, A.S., Savage, K., Kreike, B. & Reis, J.S. (2010). The molecular underpinning of lobular histological growth pattern: a genome-wide transcriptomic analysis of invasive lobular carcinomas and grade- and molecular subtype-matched invasive ductal carcinomas of no special type. J pathol, Vol.220(1), pp. 45-57.  show abstract

Klingbeil, P., Natrajan, R., Everitt, G., Vatcheva, R., Marchio, C., Palacios, J., Buerger, H., Reis, J.S. & Isacke, C.M. (2010). CD44 is overexpressed in basal-like breast cancers but is not a driver of 11p13 amplification. Breast cancer res tr, Vol.120(1), pp. 95-109.  show abstract

Turner, N., Pearson, A., Sharpe, R., Lambros, M., Geyer, F., Lopez-Garcia, M.A., Natrajan, R., Marchio, C., Iorns, E., Mackay, A., et al. (2010). FGFR1 amplification drives endocrine therapy resistance and is a therapeutic target in breast cancer. Cancer research, Vol.70(5), pp. 2085-2094.  show abstract

Molyneux, G., Geyer, F.C., Magnay, F.A., McCarthy, A., Kendrick, H., Natrajan, R., MacKay, A., Grigoriadis, A., Tutt, A., Ashworth, A., et al. (2010). BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells. Cell stem cell, Vol.7(3), pp. 403-417.  show abstract

Geyer, F.C., Weigelt, B., Natrajan, R., Lambros, M.B., de Blase, D., Vatcheva, R., Savage, K., Mackay, A., Ashworth, A. & Reis-Filho, J.S., et al. (2010). Molecular analysis reveals a genetic basis for the phenotypic diversity of metaplastic breast carcinomas. J pathol, Vol.220(5), pp. 562-573.  show abstract

Weigelt, B., Mackay, A., A'hern, R., Natrajan, R., Tan, D.S., Dowsett, M., Ashworth, A. & Reis, J.S. (2010). Breast cancer molecular profiling with single sample predictors: a retrospective analysis. Lancet oncol, Vol.11(4), pp. 339-349.  show abstract

Shiu, K.-., Natrajan, R., Geyer, F.C., Ashworth, A. & Reis-Filho, J.S. (2010). DNA amplifications in breast cancer: genotypic–phenotypic correlations. Future oncology, Vol.6(6), pp. 967-984.  show abstract

Natrajan, R., Weigelt, B., Mackay, A., Geyer, F.C., Grigoriadis, A., Tan, D.S., Jones, C., Lord, C.J., Vatcheva, R., Rodriguez-Pinilla, S.M., et al. (2010). An integrative genomic and transcriptomic analysis reveals molecular pathways and networks regulated by copy number aberrations in basal-like, HER2 and luminal cancers. Breast cancer res tr, Vol.121(3), pp. 575-589.  show abstract

Shiu, K.-., Natrajan, R., Geyer, F.C., Ashworth, A. & Reis-Filho, J.S. (2010). DNA amplifications in breast cancer: genotypic-phenotypic correlations. Future oncology, Vol.6(6), pp. 967-984.  show abstract

Geyer, F.C., Lambros, M.B., Natrajan, R., Mehta, R., Mackay, A., Savage, K., Parry, S., Ashworth, A., Badve, S. & Reis, J.S., et al. (2010). Genomic and immunohistochemical analysis of adenosquamous carcinoma of the breast. Modern pathol, Vol.23(7), pp. 951-960.  show abstract

Weigelt, B., Mackay, A., Natrajan, R., Tan, D.S., Dowsett, M., Ashworth, A. & Reis-Filho, J.S. (2010). The importance of gene-centring microarray data – Authors' reply. The lancet oncology, Vol.11(8), pp. 720-721.

Weigelt, B., Mackay, A., Natrajan, R., Tan, D.S., Dowsett, M., Ashworth, A. & Reis-Filho, J.S. (2010). The importance of gene-centring microarray data Reply. Lancet oncology, Vol.11(8), pp. 720-721.

Turner, N., Lambros, M.B., Horlings, H.M., Pearson, A., Sharpe, R., Natrajan, R., Geyer, F.C., van Kouwenhove, M., Kreike, B., Mackay, A., et al. (2010). Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets. Oncogene, Vol.29(14), pp. 2013-2023.  show abstract  full text

Lopez-Garcia, M.A., Geyer, F.C., Natrajan, R., Kreike, B., Mackay, A., Grigoriadis, A., Reis, J.S. & Weigelt, B. (2010). Transcriptomic analysis of tubular carcinomas of the breast reveals similarities and differences with molecular subtype-matched ductal and lobular carcinomas. J pathol, Vol.222(1), pp. 64-75.  show abstract

Lambros, M.B., Natrajan, R., Geyer, F.C., Lopez-Garcia, M.A., Dedes, K.J., Savage, K., Lacroix-Triki, M., Jones, R.L., Lord, C.J., Linardopoulos, S., et al. (2010). PPM1D gene amplification and overexpression in breast cancer: a qRT-PCR and chromogenic in situ hybridization study. Modern pathol, Vol.23(10), pp. 1334-1345.  show abstract

Lacroix-Triki, M., Suarez, P.H., MacKay, A., Lambros, M.B., Natrajan, R., Savage, K., Geyer, F.C., Weigelt, B., Ashworth, A. & Reis-Filho, J.S., et al. (2010). Mucinous carcinoma of the breast is genomically distinct from invasive ductal carcinomas of no special type. J pathol, Vol.222(3), pp. 282-298.  show abstract

Dedes, K.J., Lopez-Garcia, M.A., Geyer, F.C., Lambros, M.B., Savage, K., Vatcheva, R., Wilkerson, P., Wetterskog, D., Lacroix-Triki, M., Natrajan, R., et al. (2010). Cortactin gene amplification and expression in breast cancer: a chromogenic in situ hybridisation and immunohistochemical study. Breast cancer res tr, Vol.124(3), pp. 653-666.  show abstract

Dedes, K.J., Wetterskog, D., Mendes-Pereira, A.M., Natrajan, R., Lambros, M.B., Geyer, F.C., Vatcheva, R., Savage, K., Mackay, A., Lord, C.J., et al. (2010). PTEN Deficiency in Endometrioid Endometrial Adenocarcinomas Predicts Sensitivity to PARP Inhibitors. Sci transl med, Vol.2(53),  show abstract

Dedes, K.J., Wetterskog, D., Mendes-Pereira, A.M., Vatcheva, R., Natrajan, R., Lambros, M.B., Lord, C.J., Ashworth, A. & Reis-Filho, J.S. (2010). Preclinical evaluation of PARP inhibition as a treatment for endometrioid endometrial carcinomas. Journal of clinical oncology, Vol.28(15).

Tan, D.S., Lambros, M.B., Rayter, S., Natrajan, R., Vatcheva, R., Gao, Q., Marchio, C., Geyer, F.C., Savage, K., Parry, S., et al. (2009). PPM1D Is a Potential Therapeutic Target in Ovarian Clear Cell Carcinomas. Clin cancer res, Vol.15(7), pp. 2269-2280.  show abstract

Drake, K.M., Ruteshouser, E.C., Natrajan, R., Harbor, P., Wegert, J., Gessler, M., Pritchard-Jones, K., Grundy, P., Dome, J., Huff, V., et al. (2009). Loss of Heterozygosity at 2q37 in Sporadic Wilms' Tumor: Putative Role for miR-562. Clin cancer res, Vol.15(19), pp. 5985-5992.  show abstract

Natrajan, R., Lambros, M.B., Rodríguez-Pinilla, S.M., Moreno-Bueno, G., Tan, D.S., Marchió, C., Vatcheva, R., Rayter, S., Mahler-Araujo, B., Fulford, L.G., et al. (2009). Tiling path genomic profiling of grade 3 invasive ductal breast cancers. Clinical cancer research : an official journal of the american association for cancer research, Vol.15(8), pp. 2711-2722.  show abstract

Natrajan, R., Lambros, M.B., Geyer, F.C., Marchio, C., Tan, D.S., Vatcheva, R., Shiu, K.K., Hungermann, D., Rodriguez-Pinilla, S.M., Palacios, J., et al. (2009). Loss of 16q in High Grade Breast Cancer is Associated with Estrogen Receptor Status: Evidence for Progression in Tumors with a Luminal Phenotype?. Gene chromosome canc, Vol.48(4), pp. 351-365.  show abstract

Marchiò, C., Iravani, M., Natrajan, R., Lambros, M.B., Geyer, F.C., Savage, K., Parry, S., Tamber, N., Fenwick, K., Mackay, A., et al. (2009). Mixed micropapillary–ductal carcinomas of the breast: a genomic and immunohistochemical analysis of morphologically distinct components. The journal of pathology, Vol.218(3), pp. 301-315.  show abstract

Natrajan, R., Lambros, M.B., Rodriguez-Pinilla, S.M., Moreno-Bueno, G., Tan, D.S., Marchio, C., Vatcheva, R., Rayter, S., Mahler-Araujo, B., Fulford, L.G., et al. (2009). Tiling Path Genomic Profiling of Grade 3 Invasive Ductal Breast Cancers. Clinical cancer research, Vol.15(8), pp. 2711-2722.  show abstract

Marchio, C., Iravan, M., Natrajan, R., Lambros, M.B., Geyer, F.C., Savage, K., Parry, S., Tamber, N., Fenwick, K., Mackay, A., et al. (2009). Mixed micropapillary-ductal carcinomas of the breast: a genomic and immunohistochemical analysis of morphologically distinct components. Journal of pathology, Vol.218(3), pp. 301-315.  show abstract

Iorns, E., Lord, C.J., Grigoriadis, A., McDonald, S., Fenwick, K., MacKay, A., Mein, C.A., Natrajan, R., Savage, K., Tamber, N., et al. (2009). Integrated Functional, Gene Expression and Genomic Analysis for the Identification of Cancer Targets. Plos one, Vol.4(4),  show abstract  full text

Geyer, F.C., Kushner, Y.B., Lambros, M.B., Natrajan, R., Mackay, A., Tamber, N., Fenwick, K., Purnell, D., Ashworth, A., Walker, R.A., et al. (2009). Microglandular adenosis or microglandular adenoma? A molecular genetic analysis of a case associated with atypia and invasive carcinoma. Histopathology, Vol.55(6), pp. 732-743.  show abstract

Geyer, F.C., Kushner, Y.B., Lambros, M.B., Natrajan, R., Mackay, A., Tamber, N., Fenwick, K., Purnell, D., Ashworth, A., Walker, R.A., et al. (2009). Microglandular adenosis or microglandular adenoma? A molecular genetic analysis of a case associated with atypia and invasive carcinoma. Histopathology, Vol.55(6), pp. 732-743.  show abstract

Stephens, P.J., McBride, D.J., Lin, M.L., Varela, I., Pleasance, E.D., Simpson, J.T., Stebbings, L.A., Leroy, C., Edkins, S., Mudie, L.J., et al. (2009). Complex landscapes of somatic rearrangement in human breast cancer genomes. Nature, Vol.462(7276), pp. 1005-U60.  show abstract  full text

Natrajan, R., Warren, W., Messahel, B., Reis-Filho, J.S., Brundler, M.A., Dome, J.S., Grundy, P.E., Vujanic, G., Pritchard-Jones, K. & Jones, C., et al. (2008). Complex patterns of chromosome 9 alterations including the p16(INK4a) locus in Wilms tumours. J clin pathol, Vol.61(1), pp. 95-102.  show abstract

Arriola, E., Marchio, C., Tan, D.S., Drury, S.C., Lambros, M.B., Natrajan, R., Rodriguez-Pinilla, S.M., Mackay, A., Tamber, N., Fenwick, K., et al. (2008). Genomic analysis of the HER2/TOP2A amplicon in breast cancer and breast cancer cell lines. Lab invest, Vol.88(5), pp. 491-503.  show abstract

Reis-Filho, J.S., Natrajan, R., Vatcheva, R., Lambros, M.B., Marcho, C., Mahler-Araujo, B., Paish, C., Hodi, Z., Eusebi, V. & Ellis, I.O., et al. (2008). Is acinic cell carcinoma a variant of secretory carcinoma? A FISH study using ETV6 'split apart' probes. Histopathology, Vol.52(7), pp. 840-846.  show abstract

Reis-Filho, J.S., Drury, S., Lambros, M.B., Marchio, C., Johnson, N., Natrajan, R., Salter, J., Levey, P., Fletcher, O., Peto, J., et al. (2008). ESR1 gene amplification in breast cancer: a common phenomenon?. Nat genet, Vol.40(7), pp. 809-810.  show abstract

Marchio, C., Iravani, M., Natrajan, R., Lambros, M.B., Savage, K., Tamber, N., Fenwick, K., Mackay, A., Senetta, R., Di Palma, S., et al. (2008). Genomic and immunophenotypical characterization of pure micropapillary carcinomas of the breast. J pathol, Vol.215(4), pp. 398-410.  show abstract

Marchio, C., Natrajan, R., Shiu, K.K., Lambros, M.B., Rodriguez-Pinilla, S.M., Tan, D.S., Lord, C.J., Hungermann, D., Fenwick, K., Tamber, N., et al. (2008). The genomic profile of HER2-amplified breast cancers: the influence of ER status. J pathol, Vol.216(4), pp. 399-407.  show abstract

Edwards, S.L., Brough, R., Lord, C.J., Natrajan, R., Vatcheva, R., Levine, D.A., Boyd, J., Reis, J.S. & Ashworth, A. (2008). Resistance to therapy caused by intragenic deletion in BRCA2. Nature, Vol.451(7182), pp. 1111-U8.  show abstract

Natrajan, R., Little, S.E., Sodha, N., Reis-Filho, J.S., Mackay, A., Fenwick, K., Ashworth, A., Perlman, E.J., Dome, J.S., Grundy, P.E., et al. (2007). Analysis by array CGH of genomic changes associated with the progression or relapse of Wilms' tumour. J pathol, Vol.211(1), pp. 52-59.  show abstract

Little, S.E., Bax, D.A., Rodriguez-Pinilla, M., Natrajan, R., Messahel, B., Pritchard-Jones, K., Vujanic, G.M., Reis-Filho, J.S. & Jones, C. (2007). Multifaceted dysregulation of the epidermal growth factor receptor pathway in clear cell sarcoma of the kidney. Clin cancer res, Vol.13(15), pp. 4360-4364.  show abstract

Natrajan, R., Williams, R.D., Grigoriadis, A., Mackay, A., Fenwick, K., Ashworth, A., Dome, J.S., Grundy, P.E., Pritchard-Jones, K. & Jones, C., et al. (2007). Delineation of a IMb breakpoint region at IpI3 in Wilms tumors by fine-tiling oligonucleotide array CGH. Gene chromosome canc, Vol.46(6), pp. 607-615.  show abstract

Natrajan, R., Pinilla, S.M., Marchio, C., Vatcheva, R., Savage, K., Mackay, A., Fenwick, K., Tamber, N., Palacios, J., Ashworth, A., et al. (2007). Near tiling microarray-based CGH identifies CCNE1 amplification in basal-like breast cancer. Virchows arch, Vol.451(2), pp. 136-137.

Lambros, M.B., Natrajan, R. & Reis-Filho, J.S. (2007). Chromogenic and fluorescent in situ hybridization in breast cancer. Hum pathol, Vol.38(8), pp. 1105-1122.  show abstract

Tan, D.S., Lambros, M.B., Natrajan, R. & Reis, J.S. (2007). Getting it right: designing microarray (and not 'microawry') comparative genomic hybridization studies for cancer research. Lab invest, Vol.87(8), pp. 737-754.  show abstract

Marchio, C., Iravani, M., Natrajan, R., Lambros, M., James, M., Savage, K., Mackay, A., Fenwick, K., Tamber, N., Schmitt, F.C., et al. (2007). Molecular genetics and immunophenotypical characterization of micropapillary carcinomas of the breast. Virchows archiv, Vol.451(2), pp. 145-146.

Arriola, E., Lambros, M., Marchio, C., Tan, D., Natrajan, R., Rodriguez-Pinilla, S.M., Tamber, N., Fenwick, K., Mackay, A., Jones, C., et al. (2007). Her2/TOP2A amplicon in breast: A microarray-based and chromogenic in situ hybridisation analysis. Virchows archiv, Vol.451(2), pp. 141-141.

Natrajan, R., Reis-Filho, J.S., Little, S.E., Messahel, B., Brundler, M.A., Dome, J.S., Grundy, P.E., Vujanic, G.M., Pritchard-Jones, K. & Jones, C., et al. (2006). Blastemal expression of type I insulin-like growth factor receptor in Wilms' tumors is driven by increased copy number and correlates with relapse. Cancer res, Vol.66(23), pp. 11148-11155.  show abstract

Little, S.E., Vuononvirta, R., Reis, J.S., Natrajan, R., Iravani, M., Fenwick, K., Mackay, A., Ashworth, A., Pritchard-Jones, K. & Jones, C., et al. (2006). Array CGH using whole genome amplification of fresh-frozen and formalin-fixed, paraffin-embedded tumor DNA. Genomics, Vol.87(2), pp. 298-306.  show abstract

Lambros, M.B., Simpson, P.T., Jones, C., Natrajan, R., Westbury, C., Steele, D., Savage, K., Mackay, A., Schmitt, F.C., Ashworth, A., et al. (2006). Unlocking pathology archives for molecular genetic studies: a reliable method to generate probes for chromogenic and fluorescent in situ hybridization. Laboratory investigation, Vol.86(4), pp. 398-408.  show abstract

Lambros, M.B., Simpson, P.T., Jones, C., Natrajan, R., Westbury, C., Steele, D., Savage, K., Mackay, A., Schmitt, F.C., Ashworth, A., et al. (2006). Unlocking pathology archives for molecular genetic studies: a reliable method to generate probes for chromogenic and fluorescent in situ hybridization. Laboratory investigation, Vol.86(4), pp. 398-408.  show abstract

Natrajan, R., Williams, R.D., Hing, S.N., Mackay, A., Reis-Filho, J.S., Fenwick, K., Iravani, M., Valgeirsson, H., Grigoriadis, A., Langford, C.F., et al. (2006). Array CGH profiling of favourable histology Wilms tumours reveals novel gains and losses associated with relapse. J pathol, Vol.210(1), pp. 49-58.  show abstract

Natrajan, R., Little, S.E., Reis, J.S., Hing, L., Messahel, B., Grundy, P.E., Dome, J.S., Schneider, T., Vujanic, G.M., Pritchard-Jones, K., et al. (2006). Amplification and overexpression of CACNA1E correlates with relapse in favorable histology Wilms' tumors. Clin cancer res, Vol.12(24), pp. 7284-7293.  show abstract

Williams, R.D., Hing, S.N., Greer, B.T., Whiteford, C.C., Wei, J.S., Natrajan, R., Kelsey, A., Rogers, S., Campbell, C., Pritchard-Jones, K., et al. (2004). Prognostic classification of relapsing favorable histology Wilms tumor using cDNA microarray expression profiling and support vector machines. Gene chromosome canc, Vol.41(1), pp. 65-79.  show abstract


Book Chapters

Leonidou, A., Peck, B. & Natrajan, R. (2017). Identification and Validation of Driver Kinases from Next-Generation Sequencing Data. . (pp. 179-195).


Conferences

Leonidou, A., Maguire, S.L., Wai, P.T., Huang, P., Peck, B. & Natrajan, R.C. (2016). Functional characterisation of low-frequency mutations in breast cancer, BREAST CANCER RESEARCH AND TREATMENT, Vol.159(1), pp.178-179.

Wai, P., Maguire, S.L., Leonidou, A., Pemberton, H., Peck, B., Lord, C.J. & Natrajan, R. (2016). Identification of novel genetic dependencies of SF3B1 driver mutations in breast cancer, BREAST CANCER RESEARCH AND TREATMENT, Vol.159(1), p.180.

Piscuoglio, S., Ng, C.K., Cowell, C.F., Mariani, O., Martelotto, L., Natrajan, R., Lim, R.S., Maher, C.A., Vincent-Salomon, A., Weigelt, B., et al. (2016). Abstract P6-03-10: Genomic and transcriptomic heterogeneity in metaplastic breast carcinomas, Cancer Research, Vol.76(4 Supplement), p.P6-03-10.

Piscuoglio, S., Ng, C.K., Cowell, C.F., Mariani, O., Martelotto, L., Natrajan, R., Lim, R.S., Maher, C.A., Vincent-Salomon, A., Weigelt, B., et al. (2016). Genomic and transcriptomic heterogeneity in metaplastic breast carcinomas, CANCER RESEARCH, Vol.76.

Carvalho, D., Taylor, K., Burford, A., Nowak, I., Mackay, A., Vinci, M., Bjerke, L., Molinari, V., Nandhabalan, M., Ingram, W., et al. (2015). INFANTILE GLIOBLASTOMA WITH SARCOMATOUS HISTOLOGY DRIVEN BYETV6:NTRK3 FUSIONS ARE SENSITIVE TO TRK INHIBITION BY PHA-848125, NEURO-ONCOLOGY, Vol.17, p.12.

Maguire, S., Leonidou, A., Wai, P., Marchio, C., Ng, C., Sapino, A., Vincent-Salomon, A., Reis-Filho, J., Weigelt, B. & Natrajan, R., et al. (2015). Abstract A2-02: SF3B1 mutations constitute a novel therapeutic target in breast cancer, Cancer Research, Vol.75(22 Supplement 1), p.A2-02.

Martelotto, L.G., Ng, C.K., Lim, R., Piscuoglio, S., Natrajan, R., Wetterskog, D., Colombo, P.-., Reis-Filho, J.S., Vincent-Salomon, A. & Weigelt, B., et al. (2014). The Genomic Landscape of Adenoid Cystic Carcinoma of the Breast, LABORATORY INVESTIGATION, Vol.94, p.465A.

Piscuoglio, S., Ng, C.K., Martelotto, L.G., Eberle, C., Cowell, C.F., Natrajan, R., Bidard, F.-., Wilkerson, P.M., Mariani, O., Vincent-Salomon, A., et al. (2014). Papillary Carcinomas of the Breast Have Distinctive Transcriptomic Profiles and Are Not Underpinned by a Highly Recurrent Fusion Gene, MODERN PATHOLOGY, Vol.27, pp.75A-76A.

Martelotto, L.G., Ng, C.K., Lim, R., Piscuoglio, S., Natrajan, R., Wetterskog, D., Colombo, P.-., Reis-Filho, J.S., Vincent-Salomon, A. & Weigelt, B., et al. (2014). The Genomic Landscape of Adenoid Cystic Carcinoma of the Breast, MODERN PATHOLOGY, Vol.27, p.465A.

Piscuoglio, S., Ng, C.K., Martelotto, L.G., Eberle, C., Cowell, C.F., Natrajan, R., Bidard, F.-., Wilkerson, P.M., Mariani, O., Vincent-Salomon, A., et al. (2014). Papillary Carcinomas of the Breast Have Distinctive Transcriptomic Profiles and Are Not Underpinned by a Highly Recurrent Fusion Gene, LABORATORY INVESTIGATION, Vol.94, pp.75A-76A.

Maguire, S., Leonidou, A., Wai, P., Marchio, C., Ng, C., Weigelt, B., Sapino, A., Vincent-Solomon, A., Reis-Filho, J. & Natrajan, R., et al. (2014). SF3B1 K700E mutations are associated with alternative splicing in oestrogen receptor-positive breast cancer, VIRCHOWS ARCHIV, Vol.465, p.S24.

Maguire, S., Leonidou, A., Wai, P., Marchio, C., Ng, C.K., Weigelt, B., Sapino, A., Vincent-Salomon, A., Reis-Filho, J.S. & Natrajan, R., et al. (2014). SF3B1 mutations are associated with alternative splicing in ER-positive breast cancer, EUROPEAN JOURNAL OF CANCER, Vol.50, p.186.

Natrajan, R., Wilkerson, P.M., Marchio, C., Lambros, M.B., Ng, C.K., Topfer, C., Kozarewa, I., Hakas, J., Mitsopoulos, K., Hardisson, D., et al. (2013). Functional Characterisation of Fusion Genes in Micropapillary Carcinomas of the Breast, LABORATORY INVESTIGATION, Vol.93, pp.57A-58A.

Natrajan, R., Wilkerson, P.M., Marchio, C., Lambros, M.B., Ng, C.K., Topfer, C., Kozarewa, I., Hakas, J., Mitsopoulos, K., Hardisson, D., et al. (2013). Functional Characterisation of Fusion Genes in Micropapillary Carcinomas of the Breast, MODERN PATHOLOGY, Vol.26, pp.57A-58A.

Ng, C.K., Gauthier, A., Wilkerson, P.M., Lambros, M.B., Arnoud, L., Lacroix-Triki, M., Penault-Llorca, F., Baranzelli, M.C., Sastre-Garau, X., Lord, C.J., et al. (2013). Characterisation of the Genetic Heterogeneity of Invasive Breast Cancers with Heterogeneous HER2 Overexpression and Gene Amplification, MODERN PATHOLOGY, Vol.26, p.58A.

Ng, C.K., Gauthier, A., Wilkerson, P.M., Lambros, M.B., Arnoud, L., Lacroix-Triki, M., Penault-Llorca, F., Baranzelli, M.C., Sastre-Garau, X., Lord, C.J., et al. (2013). Characterisation of the Genetic Heterogeneity of Invasive Breast Cancers with Heterogeneous HER2 Overexpression and Gene Amplification, LABORATORY INVESTIGATION, Vol.93, p.58A.

Geyer, F.C., Lacroix-Triki, M., Colombo, P.-., Patani, N., Gauthier, A., Natrajan, R., Lambros, M.B., Khalifeh, I., Albarracin, C., Orru, S., et al. (2012). Molecular Evidence in Support of the Neoplastic and Precursor Nature of Microglandular Adenosis, LABORATORY INVESTIGATION, Vol.92, p.41A.

Rodrigues, D.A., Wilkerson, P., Duprez, R., Mackay, A., Lambros, M.B., Gauthier, A., Mariani, O., Mansour, M., Natrajan, R., Weigelt, B., et al. (2012). Integrative Analysis of Papillary Carcinomas of the Breast, LABORATORY INVESTIGATION, Vol.92, p.63A.

Dedes, K.J., Wilkerson, P., Wetterskog, D., Lambros, M.B., Natrajan, R., Tan, D.S., Campion-Flora, A., Rodrigues, D.N., Gauthier, A., Daley, F., et al. (2012). PARP-Inhibitor Olaparib in the Treatment of Ovarian Clear Cell Cancer: Predictors of Sensitivity and Resistance, LABORATORY INVESTIGATION, Vol.92, p.265A.

Campion-Flora, A., Hernandez, L., Wilkerson, P., Lambros, M.B., Rodrigues, D.N., Gauthier, A., Mackay, A., Natrajan, R. & Reis-Filho, J.S. (2012). Characterisation of the Repertoire of Gene Copy Number Changes and Gene Mutations in the Progression from In Situ to Invasive Breast Cancer, LABORATORY INVESTIGATION, Vol.92, pp.27A-28A.

Reis-Filho, J.S., Mackay, A., Wilkerson, P.M., Lambros, M.B., Gauthier, A., Mariani, O., Duprez, R., Rodrigues, D.N., Mandour, M., Maher, C., et al. (2012). Identification of Fusion Genes in Papillary Carcinomas of the Breast, LABORATORY INVESTIGATION, Vol.92, pp.61A-62A.

Marchio, C., Rodrigues, D.N., Wilkerson, P., Lambros, M.B., Weigelt, B., Sapino, A., Mackay, A., Maher, C., Natrajan, R. & Reis-Filho, J.S., et al. (2012). Breast Micropapillary Carcinomas: RNA-Seq and Mutation Profiling, LABORATORY INVESTIGATION, Vol.92, p.53A.

Marchio, C., Rodrigues, D.N., Wilkerson, P., Lambros, M.B., Weigelt, B., Sapino, A., Mackay, A., Maher, C., Natrajan, R. & Reis-Filho, J.S., et al. (2012). Breast Micropapillary Carcinomas: RNA-Seq and Mutation Profiling, MODERN PATHOLOGY, Vol.25, p.53A.

Campion-Flora, A., Hernandez, L., Wilkerson, P., Lambros, M.B., Rodrigues, D.N., Gauthier, A., Mackay, A., Natrajan, R. & Reis-Filho, J.S. (2012). Characterisation of the Repertoire of Gene Copy Number Changes and Gene Mutations in the Progression from In Situ to Invasive Breast Cancer, MODERN PATHOLOGY, Vol.25, pp.27A-28A.

Rodrigues, D.N., Wilkerson, P., Duprez, R., Mackay, A., Lambros, M.B., Gauthier, A., Mariani, O., Mansour, M., Natrajan, R., Weigelt, B., et al. (2012). Integrative Analysis of Papillary Carcinomas of the Breast, MODERN PATHOLOGY, Vol.25, p.63A.

Reis-Filho, J.S., Mackay, A., Wilkerson, P.M., Lambros, M.B., Gauthier, A., Mariani, O., Duprez, R., Rodrigues, D.N., Mandour, M., Maher, C., et al. (2012). Identification of Fusion Genes in Papillary Carcinomas of the Breast, MODERN PATHOLOGY, Vol.25, pp.61A-62A.

Geyer, F.C., Lacroix-Triki, M., Colombo, P.-., Patani, N., Gauthier, A., Natrajan, R., Lambros, M.B., Khalifch, I., Albarracin, C., Orru, S., et al. (2012). Molecular Evidence in Support of the Neoplastic and Precursor Nature of Microglandular Adenosis, MODERN PATHOLOGY, Vol.25, p.41A.

Duprez, R., Wilkerson, P., Lacroix-Triki, M., Lambros, M.B., Mackay, A., Hern, R.A., Gauthier, A., Colombo, P.-., Daley, F., Natrajan, R., et al. (2012). Immunophenotypic and Genomic Characterisation of Papillary Carcinomas of the Breast, MODERN PATHOLOGY, Vol.25, p.35A.

Dedes, K.J., Wilkerson, P., Wetterskog, D., Lambros, M.B., Natrajan, R., Tan, D.S., Campion-Flora, A., Rodrigues, D.N., Gauthier, A., Daley, F., et al. (2012). PARP-Inhibitor Olaparib in the Treatment of Ovarian Clear Cell Cancer: Predictors of Sensitivity and Resistance, MODERN PATHOLOGY, Vol.25, p.265A.

Lambros, M.B., Natrajan, R., Vatcheva, R., Gohlke, H., Plant, M., Muller, S. & Reis, J.S. (2011). Massarray Technology: High Throughput Method for Unlocking the Presence of Recurrent Fusion Gene in Cancer, Presented at 100th Annual Meeting of the United States and Canadian-Academy-of-Pathology, San Antonio, TX. LABORATORY INVESTIGATION, Vol.91, p.451A.

Lambros, M.B., Natrajan, R., Vatcheva, R., Gohlke, H., Plant, M., Muller, S. & Reis, J.S. (2011). Massarray Technology: High Throughput Method for Unlocking the Presence of Recurrent Fusion Gene in Cancer, Presented at 100th Annual Meeting United States-and-Canadian-Academy-of-Pathology, San Antonio, TX. MODERN PATHOLOGY, Vol.24, p.451A.

Hernandez, L., Lambros, M.B., Cabral, C., Vatcheva, R., Mackay, A., Wilkerson, P., Natrajan, R. & Reis-Filho, J.S. (2011). Genomic Analysis of Matched In Situ to Invasive Ductal Carcinomas Provides Direct Evidence for Selection of Invasive Cancer Cells with Specific Genetic Aberrations, Presented at 100th Annual Meeting United States-and-Canadian-Academy-of-Pathology, San Antonio, TX. MODERN PATHOLOGY, Vol.24, p.42A.

Mackay, A., Weigelt, B., Grigoriadis, A., Kreike, B., Natrajan, R., A'Hern, R., Tan, D.S., Dowsett, M., Ashworth, A. & Reis-Filho, J.S., et al. (2011). Identification of Molecular Subtypes of Breast Cancer Using Hierarchical Clustering: Analysis of Inter-Observer Agreement., Presented at 100th Annual Meeting United States-and-Canadian-Academy-of-Pathology, San Antonio, TX. MODERN PATHOLOGY, Vol.24, p.53A.

Natrajan, R., Wetterskog, D., Lambros, M.B., Geyer, F.C., Mackay, A., Vatcheva, R. & Reis-Filho, J.S. (2011). Functional Characterisation of the 19q12 Amplicon in Grade 3 Breast Cancers., Presented at 100th Annual Meeting United States-and-Canadian-Academy-of-Pathology, San Antonio, TX. MODERN PATHOLOGY, Vol.24, p.56A.

Wilkerson, P., Mackay, A., Lambros, M.B., Natrajan, R., Horlings, H., van de Vijver, M.J. & Reis-Filho, J.S. (2011). Identification of Drivers of the 11q13 Amplicon., Presented at 100th Annual Meeting United States-and-Canadian-Academy-of-Pathology, San Antonio, TX. MODERN PATHOLOGY, Vol.24, p.71A.

Hernandez, L., Lambros, M.B., Cabral, C., Vatcheva, R., Mackay, A., Wilkerson, P., Natrajan, R. & Reis-Filho, J.S. (2011). Genomic Analysis of Matched In Situ to Invasive Ductal Carcinomas Provides Direct Evidence for Selection of Invasive Cancer Cells with Specific Genetic Aberrations, Presented at 100th Annual Meeting of the United States and Canadian-Academy-of-Pathology, San Antonio, TX. LABORATORY INVESTIGATION, Vol.91, p.42A.

Mackay, A., Weigelt, B., Grigoriadis, A., Kreike, B., Natrajan, R., A'Hern, R., Tan, D.S., Dowsett, M., Ashworth, A. & Reis-Filho, J.S., et al. (2011). Identification of Molecular Subtypes of Breast Cancer Using Hierarchical Clustering: Analysis of Inter-Observer Agreement, Presented at 100th Annual Meeting of the United States and Canadian-Academy-of-Pathology, San Antonio, TX. LABORATORY INVESTIGATION, Vol.91, p.53A.

Natrajan, R., Wetterskog, D., Lambros, M.B., Geyer, P.C., Mackay, A., Vatcheva, R. & Reis-Filho, J.S. (2011). Functional Characterisation of the 19q12 Amplicon in Grade 3 Breast Cancers, Presented at 100th Annual Meeting of the United States and Canadian-Academy-of-Pathology, San Antonio, TX. LABORATORY INVESTIGATION, Vol.91, p.56A.

Wilkerson, P., Mackay, A., Lambros, M.B., Natrajan, R., Horlings, H., van de Vijver, M.J. & Reis-Filho, J.S. (2011). Identification of Drivers of the 11q13 Amplicon, Presented at 100th Annual Meeting of the United States and Canadian-Academy-of-Pathology, San Antonio, TX. LABORATORY INVESTIGATION, Vol.91, p.71A.

Patani, N., Dedes, K.J., Lambros, M.K., Natrajan, R., Reis-Filho, J.S. & Dowsett, M. (2011). FREQUENCY AND DISTRIBUTION OF CAVEOLIN-1 MUTATIONS IN HUMAN BREAST CANCER, Presented at Conference on Improving Care and Knowledge through Translational Research (IMPAKT) Breast Cancer, Brussels, BELGIUM. ANNALS OF ONCOLOGY, Vol.22, p.35.

Patani, N., Dedes, K.J., Lambros, M.K., Natrajan, R., Reis-Filho, J.S. & Dowsett, M. (2011). FREQUENCY AND DISTRIBUTION OF CAVEOLIN-1 MUTATIONS IN HUMAN BREAST CANCER, Presented at Conference on Improving Care and Knowledge through Translational Research (IMPAKT) Breast Cancer, Brussels, BELGIUM. ANNALS OF ONCOLOGY, Vol.22, p.35.

Weigelt, B., Geyer, F.C., Natrajan, R., Lopez-Garcia, M.A., Ahmad, A.S., Savage, K., Kreike, B. & Reis, J.S. (2010). The Molecular Underpinning of Lobular Histological Growth Pattern: A Genome-Wide Transcriptomic Analysis of Invasive Lobular Carcinomas and Grade- and Molecular Subtype-Matched Invasive Ductal Carcinomas of No Special Type, Presented at 99th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, Washington, DC. LABORATORY INVESTIGATION, Vol.90, p.77A.

Lambros, M.B., Natrajan, R., Geyer, F.C., Lopez-Garcia, M.A., Savage, K., Lacroix-Triki, M. & Reis, J.S. (2010). PPM1D Overexpression and Gene Amplification in Breast Cancers: A QRT-PCR and Chromogenic In Situ Hybridisation Study, Presented at 99th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, Washington, DC. LABORATORY INVESTIGATION, Vol.90, p.58A.

Weigelt, B., Geyer, F.C., Natrajan, R., Lopez-Garcia, M.A., Ahmad, A.S., Savage, K., Kreike, B. & Reis, J.S. (2010). The Molecular Underpinning of Lobular Histological Growth Pattern: A Genome-Wide Transcriptomic Analysis of Invasive Lobular Carcinomas and Grade- and Molecular Subtype-Matched Invasive Ductal Carcinomas of No Special Type, Presented at 99th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, Washington, DC. MODERN PATHOLOGY, Vol.23, p.77A.

Lambros, M.B., Natrajan, R., Geyer, F.C., Lopez-Garcia, M.A., Savage, K., Lacroix-Triki, M. & Reis, J.S. (2010). PPM1D Overexpression and Gene Amplification in Breast Cancers: A QRT-PCR and Chromogenic In Situ Hybridisation Study, Presented at 99th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, Washington, DC. MODERN PATHOLOGY, Vol.23, p.58A.

Lacroix-Triki, M., Saurez, P., Lambros, M.B., Natrajan, R., Mackay, A., Geyer, F.C., Ashworth, A. & Reis, J.S. (2010). Molecular Characterisation of Mucinous Carcinomas of the Breast - A Genomic Profiling Analysis, Presented at 99th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, Washington, DC. LABORATORY INVESTIGATION, Vol.90, pp.57A-58A.

Weigelt, B., Mackay, A., Natrajan, R., Tan, D.S., Ashworth, A. & Reis, J.S. (2010). Breast Cancer Molecular Subtype Classification: A Comparison of Three Microarray-Based Single Sample Predictors, Presented at 99th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, Washington, DC. LABORATORY INVESTIGATION, Vol.90, p.77A.

Weigelt, B., Mackay, A., Natrajan, R., Tan, D.S., Ashworth, A. & Reis, J.S. (2010). Breast Cancer Molecular Subtype Classification: A Comparison of Three Microarray-Based Single Sample Predictors, Presented at 99th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, Washington, DC. MODERN PATHOLOGY, Vol.23, p.77A.

Muggerud, A., Horlings, H., Lambros, M.B., Natrajan, R., Mackay, A., Ashworth, A., van de Vijver, M.J. & Reis, J.S. (2010). Integration of Microarray CGH and Expression Analysis Reveals Potential Breast Cancer Therapeutic Targets, Presented at 99th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, Washington, DC. MODERN PATHOLOGY, Vol.23, p.63A.

Lacroix-Triki, M., Saurez, P., Lambros, M.B., Natrajan, R., Mackay, A., Geyer, F.C., Ashworth, A. & Reis, J.S. (2010). Molecular Characterisation of Mucinous Carcinomas of the Breast - A Genomic Profiling Analysis, Presented at 99th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, Washington, DC. MODERN PATHOLOGY, Vol.23, pp.57A-58A.

Muggerud, A., Horlings, H., Lambros, M.B., Natrajan, R., Mackay, A., Ashworth, A., van de Vijver, M.J. & Reis-Filho, J.S. (2010). Integration of Microarray CGH and Expression Analysis Reveals Potential Breast Cancer Therapeutic Targets, Presented at 99th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, Washington, DC. LABORATORY INVESTIGATION, Vol.90, p.63A.

Natrajan, R., Geyer, F., Lambros, M.B., Lopez-Garcia, M.A., Savage, K. & Reis-Filho, J.S. (2010). Drosha and Dicer Down-Regulation in Breast Cancer: A QRT-PCR Analysis, Presented at 99th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, Washington, DC. LABORATORY INVESTIGATION, Vol.90, pp.63A-64A.

Abdel-Fatah, T.M., Powe, D.G., Lambros, M., Natrajan, R., Green, A., Reis-Filho, J.S. & Ellis, I.O. (2010). Use of High Resolution Array Comparative Genomic Hybridization (aCGH) To Identify Mouse Double Minutes 4 (Mdm4) as an Early Genetic Change in Breast Cancer Development: Evaluation of Mdm4 as a New Prognostic and Predictive Marker, Presented at 99th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, Washington, DC. LABORATORY INVESTIGATION, Vol.90, p.31A.

Natrajan, R., Geyer, F., Lambros, M.B., Lopez-Garcia, M.A., Savage, K. & Reis-Filho, J.S. (2010). Drosha and Dicer Down-Regulation in Breast Cancer: A QRT-PCR Analysis, Presented at 99th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, Washington, DC. MODERN PATHOLOGY, Vol.23, pp.63A-64A.

Abdel-Fatah, T.M., Powe, D.G., Lambros, M., Natrajan, R., Green, A., Reis-Filho, J.S. & Ellis, I.O. (2010). Use of High Resolution Array Comparative Genomic Hybridization (aCGH) To Identify Mouse Double Minutes 4 (Mdm4) as an Early Genetic Change in Breast Cancer Development: Evaluation of Mdm4 as a New Prognostic and Predictive Marker, Presented at 99th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, Washington, DC. MODERN PATHOLOGY, Vol.23, p.31A.

Natrajan, R., Rodriguez-Pinilla, S.M., Lambros, M.B., Tan, D.S., Marchio, C., Vatcheva, R., Rayter, S., Moreno-Bueno, G., Fulford, L.G., Mackay, A., et al. (2009). Molecular Profiling of Grade III Invasive Ductal Breast Cancers Identifies PPM1D Amplification as a Therapeutic Target in Luminal and HER2 Tumours, Presented at 98th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, Boston, MA. MODERN PATHOLOGY, Vol.22, p.59A.

Natrajan, R., Rodriguez-Pinilla, S.M., Lambros, M.B., Tan, D.S., Marchio, C., Vatcheva, R., Rayter, S., Moreno-Bueno, G., Fulford, L.G., Mackay, A., et al. (2009). Molecular Profiling of Grade III Invasive Ductal Breast Cancers Identifies PPM1D Amplification as a Therapeutic Target in Luminal and HER2 Tumours, Presented at 98th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, Boston, MA. LABORATORY INVESTIGATION, Vol.89, p.59A.

Reis, J.S., de Biase, D., Lambros, M.B., Geyer, F.C., Ragazzi, M., Natrajan, R., Mackay, A., Tamber, N., Fenwick, K., Ashworth, A., et al. (2009). Genomic Profiling of Mitochondria-Rich Breast Cancer, Presented at 98th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, Boston, MA. MODERN PATHOLOGY, Vol.22, p.64A.

Reis-Filho, J.S., de Biase, D., Lambros, M.B., Geyer, F.C., Ragazzi, M., Natrajan, R., Mackay, A., Tamber, N., Fenwick, K., Ashworth, A., et al. (2009). Genomic Profiling of Mitochondria-Rich Breast Cancer, Presented at 98th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, Boston, MA. LABORATORY INVESTIGATION, Vol.89, p.64A.

Natrajan, R., Lambros, M.B., Marchio, C., Tan, D.S., Vatcheva, R., Geyer, F., Shiu, K.K., Hungermann, D., Rodriguez-Pinilla, S.M., Palacios, J., et al. (2009). Loss of 16q in High Grade Breast Cancer Is Associated with ER Status: Evidence for Progression in Luminal Tumours?, Presented at 98th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, Boston, MA. LABORATORY INVESTIGATION, Vol.89, p.59A.

Natrajan, R., Lambros, M.B., Marchio, C., Tan, D.S., Vatcheva, R., Geyer, F., Shiu, K.K., Hungermann, D., Rodriguez-Pinilla, S.M., Palacios, J., et al. (2009). Loss of 16q in High Grade Breast Cancer Is Associated with ER Status: Evidence for Progression in Luminal Tumours?, Presented at 98th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, Boston, MA. MODERN PATHOLOGY, Vol.22, p.59A.

Abdel-Fatah, T.M., Powe, D.G., Lambros, M., Natrajan, R., Reis-Filho, J.S. & Ellis, I.O. (2009). High Resolution Array Comparative Genomic Hybridization (aCGH) of Breast Carcinoma Identifies Mouse Double Minutes 4 (Mdm4) as One of the Early Genetic Changes in Breast Cancer Development: Mdm4 Is a New Independent Prognostic and Predictive Marker, Presented at 32nd Annual San Antonio Breast Cancer Symposium, San Antonio, TX. CANCER RESEARCH, Vol.69(24), p.705S.

Turner, N., Lambros, M., Horlings, H., Pearson, A., Sharpe, R., Mackay, A., Natrajan, R., Geyer, F., van Kouwenhove, M., Kreike, B., et al. (2009). Integrative Molecular Profiling of Triple Negative Breast Cancers Identifies Potential Therapeutic Targets Including Amplifications of FGFR2, Presented at 32nd Annual San Antonio Breast Cancer Symposium, San Antonio, TX. CANCER RESEARCH, Vol.69(24), p.695S.

Reis-Filho, J.S., Natrajan, R., Vatcheva, R., Lambros, M.B., Marchio, C., Mahler-Araujo, B., Iravani, M., Paish, C., Hodi, Z., Eusebi, V., et al. (2008). Is acinic cell carcinoma a variant of secretory carcinoma? A FISH study using ETV6 'Split apart' probes, Presented at 97th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, Denver, CO. LABORATORY INVESTIGATION, Vol.88, p.51A.

Reis-Filho, J.S., Natrajan, R., Vatcheva, R., Lambros, M.B., Marchio, C., Mahler-Raujo, B., Iravani, M., Paish, C., Hodi, Z., Eusebi, V., et al. (2008). Is acinic cell carcinoma a variant of secretory carcinoma? A FISH study using ETV6 'split apart' probes, Presented at 97th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, Denver, CO. MODERN PATHOLOGY, Vol.21, p.51A.

Marchio, C., Iravani, M., Natrajan, R., Lambros, M.B., James, M., Savage, K., Mackay, A., Fenwick, K., Tamber, N., Schmitt, F.C., et al. (2007). Molecular genetics and immunophenotypical characterisation of micropapillary carcinomas of the breast, Presented at 30th Annual San Antonio Breast Cancer Symposium, San Antonio, TX. BREAST CANCER RESEARCH AND TREATMENT, Vol.106, p.S286.

Natrajan, R., Rodriguez-Pinilla, S.M., Marchio, C., Moreno-Bueno, G., Vatcheva, R., Mahler-Araujo, B., Lambros, M.B., Mackay, V.A., Palacios, J., Ashworth, A., et al. (2007). Array-CGH identifies CCNE1 amplification in ER/HER2 negative breast cancers, Presented at 30th Annual San Antonio Breast Cancer Symposium, San Antonio, TX. BREAST CANCER RESEARCH AND TREATMENT, Vol.106, p.S285.

Arriola, E., Lambros, M.B., Marchio, C., Tan, D., Natrajan, R., Rodrigvez-Pinilla, S.M., Tamber, N., Fenwick, K., Mackay, A., Jones, C., et al. (2007). HER2/TOP2A amplicon in breast cancer: a microarray-based and chromogenic in situ hybridisation analysis, Presented at 30th Annual San Antonio Breast Cancer Symposium, San Antonio, TX. BREAST CANCER RESEARCH AND TREATMENT, Vol.106, pp.S285-S286.

Lambros, M.B., Simpson, P.T., Jones, C., Natrajan, R., Westbury, C., Steele, D., Savage, K., MacKay, A., Schmitt, F.C., Ashworth, A., et al. (2006). Unlocking pathology archives for molecular genetic studies: A reliable method to generate probes for chromogenic and fluorescent in situ hybridisation, Presented at 26th International Congress of the International-Academy-of-Pathology, Montreal, CANADA. MODERN PATHOLOGY, Vol.19, pp.139-140.

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