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Journal Articles

Campbell, J., Ryan, C.J., Brough, R., Bajrami, I., Pemberton, H.N., Chong, I.Y., Costa-Cabral, S., Frankum, J., Gulati, A., Holme, H., et al. (2016). Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines. Cell reports, Vol.14(10), pp. 2490-2501.  show abstract  full text

Workman, P., Clarke, P.A. & Al-Lazikani, B. (2016). Blocking the survival of the nastiest by HSP90 inhibition. Oncotarget, Vol.7(4), pp. 3658-3661.  show abstract  full text

Tym, J.E., Mitsopoulos, C., Coker, E.A., Razaz, P., Schierz, A.C., Antolin, A.A. & Al-Lazikani, B. (2016). canSAR: an updated cancer research and drug discovery knowledgebase. Nucleic acids research, Vol.44(D1), pp. 938-943.  show abstract  full text

Pearl, L.H., Schierz, A.C., Ward, S.E., Al-Lazikani, B. & Pearl, F.M. (2015). Therapeutic opportunities within the DNA damage response. Nature reviews cancer, Vol.15(3), pp. 166-180.  show abstract

Mitsopoulos, C., Schierz, A.C., Workman, P. & Al-Lazikani, B. (2015). Distinctive Behaviors of Druggable Proteins in Cellular Networks. Plos computational biology, Vol.11(12), pp. e1004597-e1004597.  show abstract  full text

Al-Lazikani, B., Banerji, U. & Workman, P. (2012). Combinatorial drug therapy for cancer in the post-genomic era. Nature biotechnology, Vol.30(7), pp. 679-692.  show abstract

Patel, M.N., Halling-Brown, M.D., Tym, J.E., Workman, P. & Al-Lazikani, B. (2012). Objective assessment of cancer genes for drug discovery. Nature reviews drug discovery, Vol.12(1), pp. 35-50.  show abstract

Halling-Brown, M.D., Bulusu, K.C., Patel, M.N., Tym, J.E. & Al-Lazikani, B. (2012). canSAR: an integrated cancer public translational research and drug discovery resource. Nucleic acids research, Vol.40(D1), pp. 947-956.  show abstract  full text

Gaulton, A., Bellis, L.J., Bento, A.P., Chambers, J., Davies, M., Hersey, A., Light, Y., McGlinchey, S., Michalovich, D., Al-Lazikani, B., et al. (2012). ChEMBL: a large-scale bioactivity database for drug discovery. Nucleic acids research, Vol.40(D1), pp. 1100-1107.  show abstract  full text

Berriman, M., Haas, B.J., LoVerde, P.T., Wilson, R.A., Dillon, G.P., Cerqueira, G.C., Mashiyama, S.T., Al-Lazikani, B., Andrade, L.F., Ashton, P.D., et al. (2009). The genome of the blood fluke Schistosoma mansoni. Nature, Vol.460(7253), pp. 352-U65.  show abstract  full text

Aguero, F., Al-Lazikani, B., Aslett, M., Berriman, M., Buckner, F.S., Campbell, R.K., Carmona, S., Carruthers, I.M., Chan, A.W., Chen, F., et al. (2008). INNOVATION Genomic-scale prioritization of drug targets: the TDR Targets database. Nat rev drug discov, Vol.7(11), pp. 900-907.  show abstract

Overington, J.P., Al-Lazikani, B. & Hopkins, A.L. (2006). Opinion - How many drug targets are there?. Nat rev drug discov, Vol.5(12), pp. 993-996.  show abstract

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Division of Cancer Therapeutics

The Division of Cancer Therapeutics has an unrivalled track record at discovering novel cancer treatments and biomarkers.

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