Professor Uwe Oelfke’s team is researching ways of using modern hardware to improve the delivery of targeted radiotherapy.
Professor Uwe Oelfke is combining recent developments in cancer biology, cancer therapeutics and medical physics in order to improve radiotherapy treatment and planning. He has had a varied career spanning theoretical nuclear physics and finally medical physics.
Working in the Centre for Cancer Imaging (CCI), I facilitate biological experiments for scientists (usually with a non-biological background) who are developing imaging biomarkers to monitor treatment response. Particular interests include tumour hypoxia and molecular mechanisms of therapy resistance. As the Deputy CCI Lab Manager I also contribute to the efficient operation of the CCI’s research facilities.
I work jointly at the Royal Marsden Hospital and the ICR as a radiotherapy physicist with an interest in adaptive radiotherapy techniques. I have worked on the clinical implementation of the Elekta Unity MR-linac at the RMH with a focus on adaptive re-planning strategies and workflows.
I am a Postdoctoral Training Fellow working on distortion-less diffusion-weighted MRI for the Unity MR-Linac system. Another research interest to me is characterization of intravoxel incoherent motion with tailored diffusion-weighting gradient profiles. To achieve this, I use MR pulse programming, which I learned during my PhD on MR Neurography.
Dr Simeon Nill, is a clinical scientist who specialises in ways of targeting radiotherapy that take into account tumour movement.